(R)-1-[(S)-2-Di-(4-methoxy-3,5-dimethylphenyl-phosphino)ferrocenyl]-ethyl-di-tert-butyl-phosphine - Names and Identifiers
(R)-1-[(S)-2-Di-(4-methoxy-3,5-dimethylphenyl-phosphino)ferrocenyl]-ethyl-di-tert-butyl-phosphine - Physico-chemical Properties
Molecular Formula | C33H47O2P2.C5H5.Fe
|
Molar Mass | 658.62 |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
(R)-1-[(S)-2-Di-(4-methoxy-3,5-dimethylphenyl-phosphino)ferrocenyl]-ethyl-di-tert-butyl-phosphine - Risk and Safety
WGK Germany | 3 |
HS Code | 29319090 |
(R)-1-[(S)-2-Di-(4-methoxy-3,5-dimethylphenyl-phosphino)ferrocenyl]-ethyl-di-tert-butyl-phosphine - Introduction
(2R)-1-[(1R)-1-[BIS(1,1-DIMETHYLETHYL)PHOSPHINO]ETHYL]-2-[BIS(4-METHOXY-3,5-DIMETHYLPHENYL)PHOSPHINO]FERROCENE ((2R)-1-[(1R)-1-[BIS (1,1-DETYL) -3 PHOSPHINO] MEETHYLE2, 5-DIMETHYLPHENYL)PHOSPHINO]FERROCENE) is a chiral organic compound with the following properties:
-Appearance: Yellow solid
-Molecular formula: C_52H_64FeO_2P_2
-Molecular weight: 813.80g/mol
-Melting point: about 200-205°C
-Solubility: Soluble in common organic solvents such as chloroform, dichloromethane and dimethyl sulfoxide
The main use of this compound is as a catalyst, especially in organic synthesis reactions, such as asymmetric catalytic reactions and asymmetric reduction reactions. Its chiral structure makes it have good catalytic properties in asymmetric synthesis.
The preparation method generally involves the following steps:
1. Synthesis of a series of intermediate compounds, including p-benzidine, bis-tert-butyl phosphine compounds and bis (4-methoxy-3, 5-dimethylphenyl) phosphine compounds.
2. These intermediate compounds were subjected to two phosphorylation reactions, first reacting with (1R)-1-[BIS(1,1-DIMETHYLETHYL)PHOSPHINO]ETHYL, and then reacting with BIS(4-METHOXY-3,5-DIMETHYLPHENYL)PHOSPHINO.
3. Finally, the resulting catalyst is separated and purified.
Regarding safety information, this compound has no reported safety issues under general use conditions. However, because it is an organic compound and may be toxic, use should follow laboratory safety practices, such as wearing appropriate personal protective equipment and operating in a well-ventilated area. In addition, it is recommended that this compound be properly stored and handled to avoid the risk of fire and environmental pollution.
Last Update:2024-04-10 22:29:15